All Children’s Hospital in St. Petersburg to use $2.8 million grant to expand pediatric blood-clot study

St. Petersburg’s Johns Hopkins All Children’s Hospital will apply a recent $2.8 million grant to expand its global-scale clinical trial involving blood clots in young patients. All Children's Hospital, which received the funding in collaboration with Johns Hopkins University from the National Institutes of Health, will be expanding its Kids-DOTT study.

St. Petersburg’s Johns Hopkins All Children’s Hospital will apply a recent $2.8 million grant to expand its global-scale clinical trial involving blood clots in young patients.

All Children's Hospital, which received the funding in collaboration with Johns Hopkins University from the National Institutes of Health (NIH), will be expanding its Kids-DOTT study that focuses on calibrating treatment duration for infants, children and teens who receive anti-clotting medication following vein blood clots. The Kids-DOTT study is one of the largest pediatric blood studies on record.

“This NIH grant will expand ongoing research to improve the safety and reduce the costs of anti-clotting therapy that is needed after children leave the hospital,” Jonathan Ellen, president, CEO and physician-in-chief of Johns Hopkins All Children’s Hospital and vice dean and professor of pediatrics at Johns Hopkins University School of Medicine, said.

The analysis involves over 40 different children’s hospitals worldwide and researchers estimate a total enrollment of over 800. To date, approximately 280 children are signed up.

“Receiving this grant from the NIH underscores our commitment to clinical care and research focused on providing safe, high-value care and improving outcomes to benefit children everywhere,” Ellen said.

Statistics show that the incidence of blood clots among children is 1 in every 10,000, with 1 in every 200 hospitalized individuals affected.

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